Inflammation of the pancreas (pancreatitis) can produce signs of depression, loss of appetite, and vomiting. In severe cases pain in the abdomen and collapse with shock can occur. A chronic condition with mild signs is also sometimes seen which may last for many weeks.

The specific cause of pancreatitis is unknown. Viruses and bacteria have been isolated from the pancreas of effected animals however these may be secondary to other more generalized infections. Diet is thought to play a role as pancreatitis is often associated with the feeding of a very fatty meal. The condition is more common in middle aged, overweight animals. High blood fat (hyperlipoproteinaemia) is also a common finding in animals with pancreatitis. A number of drugs and other experimental causes have been suggested but the evidence is inconclusive.

Diagnosis is usually confirmed by blood tests which looks for increases in levels of pancreatic enzymes amylase and lipase. Although the level of these enzymes can be effected by other diseases and some drugs, a two to three fold rise is considered strong evidence of pancreatitis. Ultrasound is also proving useful to identify a swollen pancreas.

Treatment depends on the severity of signs. Acute cases require intravenous fluids (drip) and all animals are fasted for several days. There are no specific drugs for treating pancreatitis however corticosteroids and antibiotics and often used to prevent infection and reduce inflammation.

Long term therapy and prevention of recurrences is based on feeding low fat diets.